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🎓Second-semester organic chemistry · AP-equivalent rigor

Master Organic Chemistry 2

Second-semester organic chemistry at AP-equivalent rigor — pericyclic reactions, the full aromatic/carbonyl/acyl-substitution machinery, enolate condensations, biomolecules, advanced 2D NMR, and full retrosynthetic planning. Includes a 1–5 AP-equivalent score predictor.

Need to review fundamentals? ← Back to Organic Chemistry 1

Organic Chemistry 2 Curriculum

6 units · 17 topics · expanded for AP-equivalent depth

Unit 1 · Conjugation, Pericyclic & Aromatics

  • Conjugated dienes; 1,2 vs 1,4 addition
  • Diels-Alder & pericyclic reactions (FMO)
  • Aromaticity & Hückel's rule
  • EAS: directing & activating effects
  • Nucleophilic Aromatic Substitution (SNAr & benzyne)
  • Phenols & quinones

Unit 2 · Carbonyls & Acyl Substitution

  • Aldehydes & ketones (NaBH₄, Grignard, Wittig, acetals)
  • Carboxylic acid derivatives & their reactivity ladder

Unit 3 · Enolates & α-Substitution

  • Enol/enolate formation; LDA kinetic enolates
  • Aldol & Claisen condensations (incl. Dieckmann)
  • Michael addition & Robinson annulation

Unit 4 · Amines & Nitrogen Chemistry

  • Amine basicity, synthesis, alkylation/acylation
  • Diazonium salts & Sandmeyer chemistry

Unit 5 · Biomolecules

  • Carbohydrates (Fischer/Haworth, anomers, glycosides)
  • Amino acids, peptides & protein structure
  • Lipids & nucleic acids

Unit 6 · Advanced Spectroscopy & Synthesis

  • Advanced & 2D NMR: DEPT, COSY, HSQC, HMBC, NOESY
  • Multi-step synthesis & retrosynthetic analysis (synthons, FGI, protecting groups)

About the AP-Equivalent Score (1–5)

Organic Chemistry 2 is taught at AP-equivalent depth. The score predictor blends 70% quiz performance and 30% topic mastery rate, then maps the result onto the same 1–5 scale used for AP Chemistry — so you can interpret your standing the way you would for any other AP science.

  • • 5 — Top performance (≥ 85%): synthesis-ready, exam-confident.
  • • 4 — Strong (≥ 70%): solid mechanisms; refine spectroscopy.
  • • 3 — Passing (≥ 55%): foundational; rebuild carbonyl/aromatic chemistry.
  • • 2 — Below passing (≥ 35%): focused remediation needed.
  • • 1 — Beginning (< 35%): work through the lessons end-to-end.

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