## The Cell Cycle Overview

Part 1 of 7 — The Cell Cycle Overview

1. Interphase (G1, S, G2) + Mitotic phase (M)
2. Most of cell cycle spent in interphase (~90%)
3. DNA replicated during S phase
4. Cell growth in G1 and G2

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### Key Details

• Interphase (G1, S, G2) + Mitotic phase (M)
• Most of cell cycle spent in interphase (~90%)
• DNA replicated during S phase
• Cell growth in G1 and G2

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## Interphase

Part 2 of 7 — Interphase

1. G1: cell growth, organelle duplication
2. S phase: DNA replication (each chromosome → sister chromatids)
3. G2: preparation for mitosis, error checking
4. G0: cells that have exited the cell cycle

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### Key Details

• G1: cell growth, organelle duplication
• S phase: DNA replication (each chromosome → sister chromatids)
• G2: preparation for mitosis, error checking
• G0: cells that have exited the cell cycle

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## Mitosis Phases

Part 3 of 7 — Mitosis Phases

1. Prophase: chromosomes condense, spindle forms
2. Metaphase: chromosomes align at metaphase plate
3. Anaphase: sister chromatids separate, move to poles
4. Telophase: nuclear envelopes reform, chromosomes decondense

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### Key Details

• Prophase: chromosomes condense, spindle forms
• Metaphase: chromosomes align at metaphase plate
• Anaphase: sister chromatids separate, move to poles
• Telophase: nuclear envelopes reform, chromosomes decondense

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## Cytokinesis

Part 4 of 7 — Cytokinesis

1. Division of cytoplasm after mitosis
2. Animal cells: cleavage furrow (actin ring)
3. Plant cells: cell plate forms from Golgi vesicles
4. Result: two identical daughter cells

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### Key Details

• Division of cytoplasm after mitosis
• Animal cells: cleavage furrow (actin ring)
• Plant cells: cell plate forms from Golgi vesicles
• Result: two identical daughter cells

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## Cell Cycle Regulation

Part 5 of 7 — Cell Cycle Regulation

1. Checkpoints: G1, G2, and M checkpoints
2. Cyclins and CDKs control progression
3. Tumor suppressors (p53, Rb) and proto-oncogenes
4. Cancer: loss of cell cycle control

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### Key Details

• Checkpoints: G1, G2, and M checkpoints
• Cyclins and CDKs control progression
• Tumor suppressors (p53, Rb) and proto-oncogenes
• Cancer: loss of cell cycle control

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## Cell Cycle & Mitosis: Problem-Solving Workshop

Part 6 of 7 — Problem-Solving

1. Identifying mitosis stages from images
2. Predicting chromosome numbers after division
3. Analyzing cell cycle regulation failures
4. Connecting to cancer biology

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### Key Details

• Identifying mitosis stages from images
• Predicting chromosome numbers after division
• Analyzing cell cycle regulation failures
• Connecting to cancer biology

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## Cell Cycle & Mitosis: Synthesis & AP Review

Part 7 of 7 — Synthesis & AP Review

1. Mitosis vs meiosis comparison
2. Cell cycle regulation and cancer
3. Chromosome behavior during division
4. AP exam: diagram interpretation

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### Key Details

• Mitosis vs meiosis comparison
• Cell cycle regulation and cancer
• Chromosome behavior during division
• AP exam: diagram interpretation

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