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Organic Chemistry

Functional groups, stereochemistry, substitution/elimination, carbonyl chemistry, and spectroscopy

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Organic Chemistry for the MCAT

Functional Groups

Key functional groups to know:

  • Hydroxyl (-OH): Alcohols
  • Carbonyl (C=O): Aldehydes and ketones
  • Carboxyl (-COOH): Carboxylic acids
  • Amino (-NH₂): Amines
  • Thiol (-SH): Thiols

Stereochemistry

A chiral center has four different substituents. Assign R/S using Cahn-Ingold-Prelog priority rules.

  • Enantiomers: Non-superimposable mirror images (same physical properties, opposite optical rotation)
  • Diastereomers: Stereoisomers that are NOT mirror images (different physical properties)

Substitution & Elimination

ReactionStepsFavored By
SN12 (carbocation)3° substrate, polar protic solvent
SN21 (backside attack)1° substrate, strong nucleophile
E12 (carbocation)3° substrate, heat
E21 (anti-periplanar)Strong base, heat

Spectroscopy

  • IR: O-H ~3300 cm⁻¹ (broad), C=O ~1700 cm⁻¹ (sharp)
  • ¹H NMR: Chemical shift reflects electronic environment; splitting follows n+1 rule
  • Mass Spec: Molecular ion peak gives molecular weight
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📌 Related Topics in Chemical & Physical Foundations

❓ Frequently Asked Questions

What is Organic Chemistry?▾
Functional groups, stereochemistry, substitution/elimination, carbonyl chemistry, and spectroscopy
How can I study Organic Chemistry effectively?▾
Start by reading the study notes and working through the examples on this page. Then use the flashcards to test your recall. Regular review and active practice are key to retention.
Is this Organic Chemistry study guide free?▾
Yes — all study notes, flashcards, and practice problems for Organic Chemistry on Study Mondo are free to access. No account is needed.
What course covers Organic Chemistry?▾
Organic Chemistry is part of the MCAT Prep course on Study Mondo, specifically in the Chemical & Physical Foundations section. You can explore the full course for more related topics and practice resources.