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Functional groups, stereochemistry, substitution/elimination, carbonyl chemistry, and spectroscopy
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Key functional groups to know:
A chiral center has four different substituents. Assign R/S using Cahn-Ingold-Prelog priority rules.
| Reaction | Steps | Favored By | |----------|-------|------------| | SN1 | 2 (carbocation) | 3° substrate, polar protic solvent | | SN2 | 1 (backside attack) | 1° substrate, strong nucleophile | | E1 | 2 (carbocation) | 3° substrate, heat | | E2 | 1 (anti-periplanar) | Strong base, heat |
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